Efficacy of daiokanzoto in chronic constipation refractory to first-line laxatives

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Efficacy of daiokanzoto in chronic constipation refractory to first-line laxatives.

There are only a few treatment options for constipation and limited evidence of suitable treatments. Daiokanzoto (DKT) is a Kampo medicine often used clincally to treat constipation. DKT is a laxative used predominantly in Japan; however, clinical data on its efficacy and safety is lacking. Patients who used DKT, but were intolerant to either magnesium oxide (MgO; MgO group; n=16) or senna extr...

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Comparison of Pyridostigmine and bisacodyl in treatment of refractory chronic constipation.

Background: Treatment of chronic constipation is creating one of the major problems for doctors and patients. Pyridostigmine increases the gastrointestinal motility through the effects on cholinesterase. It seems that this mechanism can reduce chronic constipation. The aim of this study was to compare the effects of pyridostigmine and bisacodyl on chronic constipation. Methods: This study wa...

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Effect of laxatives and pharmacological therapies in chronic idiopathic constipation: systematic review and meta-analysis.

BACKGROUND There has been no definitive systematic review and meta-analysis to date examining the effect of laxatives and pharmacological therapies in chronic idiopathic constipation (CIC). OBJECTIVE To assess efficacy of these therapies systematically in CIC. DESIGN Systematic review and meta-analysis of randomised controlled trials (RCTs). DATA SOURCES MEDLINE, EMBASE, and the Cochrane ...

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ژورنال

عنوان ژورنال: Biomedical Reports

سال: 2016

ISSN: 2049-9434,2049-9442

DOI: 10.3892/br.2016.754